Daybue

Daybue Warnings and Precautions

• Diarrhea: Very common (occurring in most patients), sometimes persistent; may require dose interruption, reduction, or antidiarrheal management.
• Weight loss: Daybue can cause weight loss, sometimes 7% or more of body weight. Weight should be monitored regularly during treatment, and the dose interrupted, reduced, or discontinued if significant weight loss occurs.

How to Access Daybue in India: A 6-Step Process

Step 1 – Search & request your medicine: The patient or treating doctor submits a request with basic details to initiate the access process.

Step 2 – Verification & eligibility review: The team verifies availability and reviews eligibility against regulatory and clinical requirements to ensure a compliant pathway.

Step 3 – Receive quote & delivery timeline: A transparent quotation is shared, covering medicine cost, logistics, and a clear delivery timeline.

Step 4 – Regulatory approval process: Assistance is provided to secure the approvals and documentation required for legal cross-border access.

Step 5 – Temperature-controlled import & handling: The medicine is sourced and transported under strict GDP-compliant, cold-chain conditions to maintain product integrity.

Step 6 – Secure delivery: The medicine is delivered to the patient or treating hospital, with updates provided at each stage.

Note: From request to delivery, every step is designed to ensure your treatment reaches you safely, compliantly, and without unnecessary delays.

Documentation & Availability

What documents are required to import Daybue to India?

Daybue (trofinetide) oral solution may be imported in the patient's name only, by patients or government hospitals, in line with India's import regulations for unapproved medicines. The following documentation is required:

• A valid prescription from a qualified pediatric neurologist
• The patient's diagnostic reports confirming a Rett syndrome diagnosis
• Patient ID proof (issued by the Government of India)

How is the order confirmed?

The order is confirmed only after receipt and verification of a valid prescription from the doctor and, if applicable, an import permit.

Is Daybue available in India?

Daybue (trofinetide oral solution) is a prescription medicine that legally requires a doctor's prescription to be dispensed. As of current publicly available information, Daybue is not commercially marketed in India.

However, patients in India can legally access Daybue through the Named Patient Program (NPP) — an import provision that allows patients to receive medicines approved in other countries but not yet marketed in India, under a doctor's prescription and proper regulatory documentation.

Daybue received US FDA approval in March 2023 as the first treatment specifically for Rett syndrome, ensuring full transparency throughout the process.

Daybue can be made available to patients, doctors, and hospitals across major cities in India, including Gurgaon, Delhi, Bangalore, Mumbai, Navi Mumbai, Thane, Hyderabad, Mysore, Kerala, Chennai, Coimbatore, Madurai, Kolkata, Ahmedabad, Surat, Vadodara, Pune, Nagpur, Nashik, Jaipur, Udaipur, Lucknow, Kanpur, Gorakhpur, Chandigarh, Mohali, Faridabad, Noida, Ghaziabad, Kochi, Trivandrum, Kozhikode, Thrissur, Kannur, Mangalore, Bhubaneswar, Patna, Ranchi, Raipur, Guwahati, Visakhapatnam, Vijayawada, Goa, Jammu, Srinagar, Dehradun, Bhopal, Indore, Ludhiana, Amritsar, and others.

Sourcing & Delivery of Daybue

Daybue is sourced directly from authorized channels in the country of origin and shipped to India under GDP-compliant, cold-chain logistics to preserve product integrity from dispatch to delivery.

• Cold-chain shipping maintained at 2°C to 8°C throughout transit
• Real-time shipment tracking and delivery updates
• Delivery coordinated directly with the patient, family, or treating hospital

Availability of Daybue Across Major Cities in India

Named Patient Program supports access to Daybue for patients with Rett syndrome across major cities in India, coordinating documentation, sourcing, and delivery with treating specialists.

Mumbai

Patients in Mumbai can access Daybue through NPP with support from treating pediatric neurologists at the city's leading centers.

Delhi

In Delhi, NPP coordinates with hospitals and specialty neurology clinics to facilitate timely access to Daybue.

Bangalore

Bangalore's pediatric neurology centers work with NPP to support patients requiring Daybue.

Chennai

Patients in Chennai can access Daybue through NPP, with coordination between treating doctors and the program's regulatory and logistics team.

Hyderabad

Hyderabad's pediatric neurology centers support diagnosis and access coordination for Daybue through NPP.

Kolkata

NPP facilitates access to Daybue for patients in Kolkata under the guidance of treating specialists.

Pune

Patients in Pune can access Daybue through NPP with prescription-based coordination and cold-chain delivery support.

Ahmedabad

NPP supports access to Daybue for patients in Ahmedabad, working directly with treating specialists.

Kochi

Patients in Kochi and across Kerala can access Daybue through NPP's regulated import pathway.

Chandigarh

NPP coordinates access to Daybue for patients in Chandigarh and the surrounding region.

Jaipur

Patients in Jaipur can access Daybue through NPP with support from treating specialists.

Lucknow

NPP facilitates access to Daybue for patients in Lucknow and across Uttar Pradesh.

Bhubaneswar

Patients in Bhubaneswar can access Daybue through NPP's coordinated import and delivery process.

Guwahati

NPP supports access to Daybue for patients in Guwahati and across the Northeast region.

NPP also supports access for patients in other Indian cities not listed above — contact the team to check availability and timelines for your location.