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Truqap

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Truqap

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Medicine Name: Truqap
Generic Name (API): Capivasertib
Dosage Form & Strength: 160 mg, 200 mg
Route: Oral (taken by mouth, with or without food)
Drug Class: AKT inhibitor — a first-in-class, ATP-competitive inhibitor of all three AKT isoforms (AKT1/AKT2/AKT3)

Manufacturer / Innovator:

USA

Regulatory Approval:

  • US FDA
  • European Union (EMA)
  • Japan (PDMA)
  • Canada (HC)
  • and Australia (TGA)
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Truqap Uses and Indications

Truqap (capivasertib) is a targeted oral anticancer medicine known as an AKT inhibitor. AKT is a signalling protein inside cells that helps control cell growth, survival, and metabolism. In certain cancers, the PI3K/AKT/PTEN pathway becomes overactive — often because of genetic alterations in PIK3CA, AKT1, or loss of PTEN — which allows tumour cells to keep growing. Capivasertib blocks all three AKT isoforms (AKT1, AKT2, AKT3), switching off this cancer-driving signal. Because its activity depends on the tumour's biomarker profile, patients must be selected using an approved diagnostic test.

Truqap is indicated for:


  • HR-positive, HER2-negative locally advanced or metastatic breast cancer in adults with one or more PIK3CA, AKT1, or PTEN alterations (as detected by an approved test), following progression on at least one endocrine-based regimen in the metastatic setting or recurrence on or within 12 months of completing adjuvant therapy — used in combination with fulvestrant.
  • PTEN-deficient metastatic androgen pathway modulation-naïve or -sensitive (mAPMN/S) prostate cancer — previously referred to as metastatic hormone-sensitive prostate cancer (mHSPC) — where PTEN deficiency is confirmed by an authorized companion diagnostic test (VENTANA PTEN SP218 RxDx Assay), used in combination with abiraterone and prednisone.
Truqap is a prescription anticancer medicine and must be used only under the supervision of a qualified medical oncologist or uro-oncologist.

Recommended Dosage:

The recommended starting dose is 400 mg twice daily (approximately 12 hours apart) — usually given as two 200 mg tablets per dose. Treatment is continued until disease progression or unacceptable toxicity. Truqap is taken orally, with or without food, on an intermittent weekly schedule: 4 consecutive days on treatment, followed by 3 days off, repeated each week. 

Tablets should be swallowed whole. Do not chew, crush, or split them, and do not take tablets that are broken, cracked, or otherwise not intact. Where a dose reduction is required for side effects, the recommended reduced dose levels are 320 mg twice daily and then 240 mg twice daily. Because capivasertib is a CYP3A substrate, concomitant use with strong CYP3A inhibitors should be avoided; if unavoidable, or when a moderate CYP3A inhibitor is used, the dose is reduced to 320 mg twice daily on the same 4-days-on/3-days-off schedule.

Fasting glucose and HbA1c should be evaluated before starting Truqap and at regular intervals during treatment. Pregnancy status must be verified in females of reproductive potential before initiating therapy.

This information is not a treatment plan. For personalized medical advice, consult your doctor and refer to the full prescribing information.

Truqap Warnings and Precautions

  • Truqap can cause severe hyperglycemia, including diabetic ketoacidosis, which may rarely be fatal. Your doctor will monitor blood sugar before and during treatment. Report excessive thirst, frequent urination, confusion, unusual tiredness, or fruity-smelling breath immediately, especially if you have diabetes or pre-diabetes.
  • Diarrhoea is very common with Truqap and may become severe. Begin anti-diarrhoeal treatment as advised at the first sign of loose stools, drink plenty of fluids, and contact your doctor if symptoms persist or worsen, as treatment adjustments may be required.
  • Truqap may cause serious skin reactions, including Stevens-Johnson syndrome and erythema multiforme. Seek immediate medical attention if you develop rash, blistering, peeling skin, mouth or eye sores, or rash accompanied by fever during treatment with Truqap.
  • Do not use Truqap if you have a known severe allergy to capivasertib or any of its ingredients. Inform your doctor immediately if you experience swelling, difficulty breathing, severe rash, or any signs of an allergic reaction after taking Truqap.
  • Truqap may harm an unborn baby. Use effective contraception during treatment and for the recommended period after the last dose. Do not breastfeed during treatment. Discuss pregnancy or breastfeeding plans with your doctor before starting Truqap therapy.
  • Truqap may cause fatigue, nausea, vomiting, dizziness, and mouth sores. If you feel tired, dizzy, or generally unwell, avoid driving, operating machinery, or performing tasks requiring alertness until your doctor confirms it is safe.
  • Do not start, stop, or change any prescription medicines, over-the-counter products, supplements, or herbal remedies without consulting your doctor. Certain medicines, especially CYP3A inhibitors and inducers, can affect Truqap levels and may require dose adjustments.

How to Access Truqap in India: A 6-Step Process


Step 1 – Search & request your medicine: The patient or treating doctor submits a request with basic details to initiate the access process. 

Step 2 – Verification & eligibility review: The team verifies availability and reviews eligibility against regulatory and clinical requirements to ensure a compliant pathway. 

Step 3 – Receive quote & delivery timeline: A transparent quotation is shared, covering medicine cost, logistics, and a clear delivery timeline. 

Step 4 – Regulatory approval process: Assistance is provided to secure the approvals and documentation required for legal cross-border access. 

Step 5 – Quality-controlled import & handling: The medicine is sourced and transported under strict GDP-compliant, temperature-monitored conditions to maintain product integrity. 

Step 6 – Secure delivery: The medicine is delivered to the patient or treating hospital, with updates provided at each stage.

Access This Process Easily via Our App:

You can manage the entire process seamlessly through the Named Patient Program App, available on both the Play Store and App Store.
  • Track your medicine request in real-time
  • Upload documents and approvals
  • View quotations and timelines
  • Get status updates at every step
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Documentation & Availability

What documents are required to import TRUQAP to India? 

TRUQAP (capivasertib) tablets may be imported in the patient's name only, by patients or government hospitals. The following documentation is required:
  • A valid prescription from a qualified doctor
  • The patient's diagnostic reports (including biomarker/companion diagnostic test results where applicable)
  • Patient ID proof (issued by the Government of India)

How is the order confirmed?

The order is confirmed only after receipt and verification of a valid prescription from the doctor and, if applicable, an import permit.

Is TRUQAP available in India? 

TRUQAP (capivasertib) is a prescription medicine that legally requires a doctor's prescription to be dispensed. As of current publicly available information, TRUQAP is not commercially marketed in India.

However, patients in India can legally access TRUQAP through the Named Patient Program (NPP) — an import provision that allows a medicine not yet registered in India to be imported in the name of an individual patient, on the prescription of their treating physician.

Named Patient Program.com (NPP) act as a facilitator under named patient supply, providing input on:

  • Availability of Truqap in India and pathways to access it
  • Availability in Gulf countries (Bahrain, Oman, Qatar, Kuwait, Iraq, Saudi Arabia, and the UAE)
  • Truqap price in India under the NPP route
  • Sourcing from genuine, reliable channels in the USA, Europe, China, Singapore, Canada, and Australia
  • Ensuring full transparency throughout the process
TRUQAP can be made available to patients, doctors, and hospitals across major cities in India, including Gurgaon, Delhi, Bangalore, Mumbai, Navi Mumbai, Thane, Hyderabad, Mysore, Kerala, Chennai, Coimbatore, Madurai, Kolkata, Ahmedabad, Surat, Vadodara, Pune, Nagpur, Nashik, Jaipur, Udaipur, Lucknow, Kanpur, Gorakhpur, Chandigarh, Mohali, Faridabad, Noida, Ghaziabad, Kochi, Trivandrum, Kozhikode, Thrissur, Kannur, Mangalore, Bhubaneswar, Patna, Ranchi, Raipur, Guwahati, Visakhapatnam, Vijayawada, Goa, Jammu, Srinagar, Dehradun, Bhopal, Indore, Ludhiana, Amritsar, and others — and can facilitate delivery to the patient's treating hospital. Orders are confirmed only upon receipt of a valid doctor's prescription and, where applicable, an import permit.

Sourcing & Delivery of Truqap

Named Patient Program.com (NPP) can source Truqap from reliable global manufacturers and qualified pharmaceutical supply channels and facilitate supply to patients, doctors, and hospitals under applicable legal provisions. As an oral solid-dose product, Truqap is transported and stored under controlled room-temperature, GDP-compliant conditions, with tamper-evident packaging and batch traceability maintained throughout transit.

All prescriptions are dispensed and checked by registered pharmacists and dispatched from New Delhi, India, after legal requirements are fulfilled.

For Truqap cost in India and availability, contact NPP via WhatsApp at +91 98104 69557 | Toll-Free: 1800-1200-365 or email info@namedpatientprogram.com.

Availability of Truqap® Across Major Cities in India:

Patients across India can access Truqap® through regulated import pathways, with delivery arranged to the treating hospital or patient based on a valid oncologist's prescription and supporting biomarker test reports.

  • Mumbai: A major oncology hub with institutions like Tata Memorial, Mumbai, sees high demand for biomarker-driven therapies such as Truqap® for advanced breast and prostate cancer. 
  • Bangalore: With a growing network of multispecialty hospitals and molecular diagnostic capability, Bangalore supports access to global targeted therapies through structured import pathways. 
  • Delhi: As part of the Delhi NCR region, the city has a strong concentration of cancer centres, breast units, and uro-oncology specialists, making it a key location for accessing advanced imported therapies. 
  • Gurgaon: Home to leading hospitals like Medanta, Gurgaon plays an important role in facilitating access to innovative precision oncology treatments through coordinated care pathways. 
  • Noida: With proximity to Delhi and access to top hospitals, Noida patients benefit from streamlined logistics and specialist-driven treatment planning. 
  • Hyderabad: Hyderabad's advanced healthcare infrastructure and oncology expertise support patients seeking access to internationally approved targeted cancer therapies. 
  • Chennai: Known for its established medical ecosystem, Chennai attracts patients from across India for complex cancer treatments and specialised drug access. 
  • Kolkata: A key eastern healthcare hub, Kolkata offers access to advanced oncology care through leading hospitals and treatment centres. 
  • Ahmedabad: Ahmedabad's expanding healthcare sector and oncology facilities support patients requiring advanced and imported cancer therapies. 
  • Pune: With reputed hospitals and a growing cancer care infrastructure, Pune is an emerging centre for access to specialised oncology treatments. 
  • Chandigarh: Serving North India, Chandigarh provides access to advanced medical care through reputed institutions and specialist-led treatment planning. 
  • Jaipur: Jaipur's improving healthcare network enables patients to explore access to innovative cancer therapies through structured import processes. 
  • Lucknow: As a major city in North India, Lucknow supports access to advanced oncology treatments through both public and private healthcare institutions. 
  • Indore: Indore is emerging as a regional healthcare hub, offering access to specialised cancer care and modern treatment pathways. 
  • Bhopal: Patients in Bhopal can access advanced cancer treatments through the growing healthcare infrastructure and referral networks. 
  • Nagpur: Nagpur serves as a central hub for patients across Vidarbha, with increasing access to oncology care and targeted therapies. 
  • Surat: Surat's developing healthcare ecosystem supports patients seeking access to global oncology treatments through coordinated care. 
  • Patna: As a major city in Eastern India, Patna provides growing access to cancer treatment through expanding hospital networks. 
  • Coimbatore: Coimbatore is known for quality healthcare services, offering access to advanced oncology treatments in South India. 
  • Kochi: With modern hospitals and specialist care, Kochi enables patients to explore access to internationally approved cancer therapies.
Note: Access timelines may vary depending on documentation, regulatory approvals, and sourcing logistics.

Access/Buy Truqap® at Leading Hospitals in India

Truqap® is typically prescribed in advanced medical oncology and uro-oncology settings, following biomarker testing, and can be accessed at leading hospitals across India, where specialists guide treatment decisions and coordinate patient-specific access pathways.

Major Hospitals Covered:

  • Tata Memorial Centre: One of India's premier cancer institutes, Tata Memorial plays a key role in managing advanced breast and prostate cancer and guiding patients toward biomarker-directed therapies like Truqap®. 
  • AIIMS: As a leading government medical institution, AIIMS provides comprehensive cancer care and supports patients requiring access to specialised and emerging treatments. 
  • Apollo Hospitals: With a nationwide presence, Apollo Hospitals offers advanced oncology services and facilitates access to global treatment options through its extensive medical network. 
  • Fortis Healthcare: Fortis hospitals are equipped with modern cancer care facilities and multidisciplinary teams that manage complex treatment pathways for patients. 
  • Max Healthcare: Max Healthcare is known for its strong medical oncology and uro-oncology departments, providing access to innovative therapies under expert clinical supervision. 
  • Manipal Hospitals: Manipal Hospitals supports advanced cancer care through experienced specialists and structured treatment planning across multiple cities. 
  • Kokilaben Dhirubhai Ambani Hospital: A leading private hospital in Mumbai, Kokilaben Hospital offers cutting-edge oncology care and access to advanced global therapies. 
  • Medanta – The Medicity: Medanta is a renowned super-specialty hospital where complex cancer cases are managed with advanced treatment protocols and global access support. 
  • BLK-Max Super Speciality Hospital: BLK-Max provides comprehensive oncology services and supports patients seeking access to specialised treatment options. 
  • Rajiv Gandhi Cancer Institute: A dedicated cancer care centre, RGCI focuses on advanced oncology treatments and supports patients through complex treatment journeys. 
  • HCG Cancer Centre: HCG is a specialised cancer hospital network known for its focus on precision oncology and advanced treatment modalities. 
  • Narayana Health: Narayana Health combines affordability with advanced medical care, offering oncology services across multiple locations in India. 
  • Amrita Hospital: Amrita Hospital provides high-quality cancer care with a focus on patient-specific treatment and access to modern therapies. 
  • Yashoda Hospitals: Yashoda Hospitals are known for their strong oncology departments and advanced treatment infrastructure in South India. 
  • Aster Hospitals: Aster Hospitals offer integrated cancer care services and support access to innovative therapies through coordinated treatment planning. 
  • Sir Ganga Ram Hospital: A well-established hospital in Delhi, Sir Ganga Ram provides multidisciplinary cancer care supported by experienced specialists. 
  • Jaslok Hospital: Jaslok Hospital is known for its specialised medical services and advanced oncology treatment capabilities. 
  • Ruby Hall Clinic: Ruby Hall Clinic offers comprehensive cancer care and supports patients requiring advanced and imported therapies. 
  • CARE Hospitals: CARE Hospitals provide modern oncology treatment facilities and multidisciplinary care across multiple cities.
  • Global Hospitals: Global Hospitals are equipped with advanced medical technologies and oncology expertise to manage complex cancer cases.
Note: Truqap® is not stocked for direct purchase but is arranged through compliant import processes and delivered to the patient or treating hospital for patient-specific treatment.

Written By:

Nitin Goswami

Medically Reviewed By:

Shilpi Banerjee
TRUSTED BY HEALTHCARE PROFESSIONALS & HOSPITALS

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