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Vonjo

Sourced directly from the authorized manufacturer network to ensure authenticity and quality.

Ready to proceed? Start a request for Vonjo on our secure patient portal to submit your prescription, upload documents and track your approval status.

Vonjo

Supplied with complete CDSCO-approved import and customs documentation, including Form 12A & 12B, CDEC, GST Bill of Entry, Commercial Invoice, and Packing List.

Medicine Name: Vonjo
Generic Name (API): Pacritinib
Dosage Form & Strength: 100 mg
Route: Oral
Drug Class:

Manufacturer / Innovator:

USA

Regulatory Approval:

  • FDA (US)
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  • Medicines sourced from authorized manufacturers with full batch traceability

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  • EU-GDP Compliant Warehousing for secure, quality-controlled global distribution.

    EU-GDP compliant warehousing for secure, quality-controlled global distribution.

  • Temperature-Controlled Logistics for Safe and Timely Delivery

    Temperature-controlled logistics ensuring safe, reliable, and timely medicine delivery.

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Understanding Vonjo and Its Medical Uses

Vonjo (pacritinib) is a kinase inhibitor approved by the FDA under accelerated approval for the treatment of adults with intermediate or high-risk primary or secondary myelofibrosis (including post-polycythemia vera and post-essential thrombocythemia myelofibrosis) who have a platelet count below 50 x 10⁹/L.

How Vonjo Works

Vonjo inhibits JAK2 and IRAK1 signaling pathways involved in the abnormal blood cell production characteristic of myelofibrosis. Unlike some other JAK inhibitors, Vonjo is specifically indicated for patients with significant thrombocytopenia (low platelet counts), a population often excluded from other myelofibrosis treatments.

Approved Patient Population

Vonjo is intended for myelofibrosis patients with severe thrombocytopenia (platelet counts below 50 x 10⁹/L), a group with limited treatment options due to bleeding risk concerns with other therapies.

Dosage and Administration

The recommended dose of Vonjo is 200 mg taken orally twice daily, with or without food. A reduced starting dose of 100 mg twice daily is used in patients with severe hepatic impairment.

Warnings and Precautions for Vonjo

Vonjo does not carry a formal FDA boxed warning. Unlike some other JAK inhibitors, Vonjo's current label does not carry the class-wide JAK-inhibitor boxed warning for MACE, thrombosis, malignancy, and mortality — these risks appear as standard (non-boxed) Warnings and Precautions. Patients and prescribers should be aware of the following important safety information.

Hemorrhage

Bleeding events have been reported. Vonjo should be avoided in patients with active bleeding, and treatment should be held before planned surgery.

Diarrhea

Diarrhea is commonly reported and may require dose reduction or temporary interruption.

QT Prolongation

Vonjo should be avoided in patients with a baseline QTc greater than 480 msec, and electrolyte abnormalities should be corrected before starting treatment.

Cardiovascular and Thrombotic Risk

Major adverse cardiovascular events and thrombosis have been reported, particularly in patients who smoke or have other cardiovascular risk factors.

How to Access Vonjo in India: A 6-Step Process

Step 1 – Search & request your medicine: The patient or treating doctor submits a request with basic details to initiate the access process.

Step 2 – Verification & eligibility review: The team verifies availability and reviews eligibility against regulatory and clinical requirements to ensure a compliant pathway.

Step 3 – Receive quote & delivery timeline: A transparent quotation is shared, covering medicine cost, logistics, and a clear delivery timeline.

Step 4 – Regulatory approval process: Assistance is provided to secure the approvals and documentation required for legal cross-border access.

Step 5 – Temperature-controlled import & handling: The medicine is sourced and transported under strict GDP-compliant conditions to maintain product integrity.

Step 6 – Secure delivery: The medicine is delivered to the patient or treating hospital, with updates provided at each stage.

Note: From request to delivery, every step is designed to ensure your treatment reaches you safely, compliantly, and without unnecessary delays.

Documentation and Availability of Vonjo

Vonjo is manufactured and marketed by Sobi, Inc. (Swedish Orphan Biovitrum). It is sourced through authorized distribution channels for patients seeking named-patient import into India.

Required Documentation

Patients typically need a valid prescription from a treating hematologist confirming myelofibrosis diagnosis and platelet count. NPP's regulatory team assists in preparing and verifying the documentation needed for a compliant import.

Availability

As an FDA-approved therapy for myelofibrosis patients with severe thrombocytopenia, Vonjo is sourced through authorized channels and imported under GDP-compliant logistics to preserve product quality throughout transit.

Sourcing and Delivery of Vonjo

NPP sources Vonjo directly from authorized pharmaceutical distributors to ensure product authenticity and full traceability. Every shipment is handled under Good Distribution Practice (GDP) conditions from origin to the patient's doorstep.

Storage and Handling

Vonjo should be stored at room temperature, below 30°C, in its original package to protect from light, and this condition is maintained throughout transit.

Delivery Timelines

Once documentation and regulatory approvals are in place, delivery timelines are communicated transparently at the time of quotation, accounting for import clearance and last-mile logistics to the patient's city.

Availability of Vonjo Across Major Cities in India

Patients across India can access Vonjo through NPP's regulated import pathway, with hematology specialists in major cities supporting the treatment process.

Mumbai

Leading hospitals in Mumbai support hematology care coordination and documentation for Vonjo access.

Delhi

Delhi's major hospitals assist patients with prescription support and documentation for Vonjo.

Bangalore

Bangalore's specialist network offers access coordination for eligible myelofibrosis patients seeking Vonjo.

Chennai

Chennai-based hematology specialists coordinate Vonjo access alongside comprehensive myelofibrosis care.

Hyderabad

Hyderabad's care institutions support patients pursuing Vonjo therapy.

Kolkata

Kolkata's specialist centers help coordinate documentation and treatment access for Vonjo.

Pune

Pune-based specialists assist with prescription support and Vonjo treatment planning.

Ahmedabad

Ahmedabad's specialty hospitals support the import and treatment process for Vonjo.

Kochi

Kochi's specialist units assist patients with the documentation needed for Vonjo access.

Chandigarh

Chandigarh's care centers support Vonjo treatment coordination for patients from North India.

Jaipur

Jaipur's specialists help patients navigate the Vonjo access process.

Lucknow

Lucknow-based centers assist patients pursuing Vonjo therapy.

Bhubaneswar

Bhubaneswar's institutions support access to Vonjo for eligible patients.

Guwahati

Guwahati's specialists help coordinate Vonjo access for patients across the Northeast.

Patients in other cities across India can also access Vonjo through NPP's nationwide coordination network.

Author Details

Nitin Goswami

Written By

Nitin Goswami

Deputy Manager – Content & Social Media, Ikris Pharma Network

Sources: FDA

Dr. Chirag C Shah

Medically Reviewed By

Dr. Chirag C Shah

MBBS

Last Updated: 15 September 2026

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