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Olgotrelvir

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Olgotrelvir

Supplied with complete CDSCO-approved import and customs documentation, including Form 12A & 12B, CDEC, GST Bill of Entry, Commercial Invoice, and Packing List.

Medicine Name: Olgotrelvir
Generic Name (API): Olgotrelvir Sodium
Dosage Form & Strength: 0.2 g
Route: Oral
Drug Class: Antiviral, SARS-CoV-2 main protease (3CL) and cathepsin L inhibitor

Manufacturer / Innovator:

China

Regulatory Approval:

  • NMPA (China)
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What Is Olgotrelvir Used For?

Olgotrelvir is an oral antiviral capsule for COVID-19, developed and made in China by Zhejiang ACEA Pharmaceutical, where it is sold as 奥维宁® (olgotrelvir sodium capsules). It is a short, five-day course, taken on its own, without a second "booster" medicine.

China's National Medical Products Administration (NMPA) gave it conditional approval in late October 2025 (announced 5 November 2025) for:

  • Adults with mild to moderate COVID-19 (SARS-CoV-2 infection)

Conditional approval means the company must still submit further study results to the NMPA. The Chinese label also points out that the virus keeps changing, so doctors should take the variants in circulation into account.

It is a prescription infectious disease medicine and should only be used under a doctor's care.

How It Works

Once swallowed, olgotrelvir is turned into its active form, AC1115. This blocks the virus's main protease (Mpro, also called 3CL protease), an enzyme the virus needs to build new copies of itself. It also blocks cathepsin L, a protein in our own cells that the virus uses to get inside them. Acting on two targets at once is why the company describes it as a dual-action antiviral.

What the Trial Showed

The phase 3 trial (MPR-COV-301CN), published in NEJM Evidence in 2024, enrolled 1,212 adults in China with mild or moderate COVID-19 who were not in hospital. Most were young (median age 33), vaccinated and had mild illness.

  • Symptoms cleared faster: a median of 205 hours (about 8.5 days) against 264 hours (11 days) on placebo, roughly 2.5 days sooner
  • The virus level in the nose and throat fell further by day 4 (an extra 0.8 log10 copies/mL compared with placebo)
  • In people with risk factors for severe illness, symptoms resolved about 54 hours sooner

Recommended Dosage

  • 600 mg (three 0.2 g capsules) twice a day, at least 8 hours apart
  • Taken on an empty stomach, because a high-fat meal lowers how much of the medicine is absorbed
  • For 5 days in a row (30 capsules in total)
  • Start as soon as possible, within 3 days of the first symptoms

It has not been studied in people with liver or kidney problems, or in anyone under 18. Your doctor decides whether it is suitable for you.

This information is not a treatment plan. For personalized medical advice, consult your doctor and refer to the full prescribing information.

Warnings and Precautions

Allergy: it must not be taken by anyone allergic to olgotrelvir or any of the capsule's ingredients. The capsules contain sodium bisulfite, so people who are sensitive to sulfites should use them with caution.

  • Timing matters: the label says to start within 3 days of the first symptoms. It was studied only in people who were not in hospital, not in severe COVID-19.
  • Liver and kidneys: it has not been studied in people with liver or kidney impairment, so the label cannot give dose advice for them.
  • Older adults: people aged 60 and over were included in the trial, but their numbers were small.
  • Pregnancy: there is no human data, so it is not recommended in pregnancy. Women who could become pregnant should use effective contraception during treatment and for 7 days after the last dose.
  • Breastfeeding: the label advises not to breastfeed during treatment and for 7 days after.
  • Other medicines: laboratory and clinical studies suggest a low risk of drug interactions, but always give your doctor a full list of what you take.

Side effects in the trial: side effects judged to be caused by the medicine occurred in 14.2% of people on olgotrelvir and 9.2% on placebo, and 97.7% of them were mild or moderate. The most common were raised triglycerides (blood fats, 3.1% vs 2.0%), skin rash (2.5% vs 0%) and nausea (1.3% vs 0.2%). No serious side effects linked to the medicine and no deaths were reported.

How to Access Olgotrelvir in India: A 6-Step Process

Step 1 – Search & request your medicine: The patient or treating doctor submits a request with basic details to initiate the access process.

Step 2 – Verification & eligibility review: The team verifies availability and reviews eligibility against regulatory and clinical requirements to ensure a compliant pathway.

Step 3 – Receive quote & delivery timeline: A transparent quotation is shared, covering medicine cost, logistics, and a clear delivery timeline.

Step 4 – Regulatory approval process: Assistance is provided to secure the approvals and documentation required for legal cross-border access.

Step 5 – Temperature-controlled import & handling: The medicine is sourced and transported under strict GDP-compliant conditions to maintain product integrity.

Step 6 – Secure delivery: The medicine is delivered to the patient or treating hospital, with updates provided at each stage.

Note: From request to delivery, every step is designed to ensure your treatment reaches you safely, compliantly, and without unnecessary delays.

Documentation & Availability

What documents are required to import Olgotrelvir to India?

The capsules can be imported only in the patient's name, by the patient or a government hospital, in line with India's import regulations for unapproved medicines. You will need:

  • A valid prescription from a qualified physician or infectious disease specialist
  • A positive COVID-19 test report and a note of when symptoms started
  • Patient ID proof (issued by the Government of India)

How is the order confirmed?

Once we have received and checked a valid prescription and, where needed, an import permit. Because the course should start within three days of symptoms, we tell you the realistic delivery time before you order.

Is Olgotrelvir available in India?

No. It is approved only in China. It has no CDSCO approval, it is not sold in Indian pharmacies, and the US FDA and European Medicines Agency have not approved it either.

Patients can still get it legally through the Named Patient Program (NPP), which allows a medicine not registered in India to be imported for one specific patient on a prescription. We also help with other imported antivirals, such as Livtencity and Foscavir, which are used for different viral infections.

It can be made available to patients, doctors, and hospitals across major cities in India, including Gurgaon, Delhi, Bangalore, Mumbai, Navi Mumbai, Thane, Hyderabad, Mysore, Kerala, Chennai, Coimbatore, Madurai, Kolkata, Ahmedabad, Surat, Vadodara, Pune, Nagpur, Nashik, Jaipur, Udaipur, Lucknow, Kanpur, Gorakhpur, Chandigarh, Mohali, Faridabad, Noida, Ghaziabad, Kochi, Trivandrum, Kozhikode, Thrissur, Kannur, Mangalore, Bhubaneswar, Patna, Ranchi, Raipur, Guwahati, Visakhapatnam, Vijayawada, Goa, Jammu, Srinagar, Dehradun, Bhopal, Indore, Ludhiana, Amritsar, and others — and can facilitate delivery to the patient's treating hospital. Orders are confirmed only after receipt of a valid doctor's prescription and an import permit, where applicable.

Sourcing & Delivery

NamedPatientProgram.com (NPP) sources this medicine through the manufacturer's authorised supply channels in China and arranges supply to patients, doctors, and hospitals under applicable legal provisions. Each box holds 30 capsules of 0.2 g (five blister strips of six), which is exactly one full five-day course. The capsules are kept sealed, away from light and below 25°C, and travel in their original packs under temperature-controlled shipping. All prescriptions are dispensed and checked by registered pharmacists and dispatched from New Delhi, India, after legal requirements are fulfilled.

For the current cost in India and availability, contact NPP via WhatsApp at +91 98104 69557 | Toll-Free: 1800-1200-365 or email info@namedpatientprogram.com.

Availability Across Major Cities in India

Patients across India can access this medicine through regulated import pathways, with delivery arranged to the patient or the treating clinic on a valid doctor's prescription.

Delhi

Being close to our New Delhi dispatch point gives patients in the capital the shortest delivery time, which matters for a medicine that should be started early.

Mumbai

Physicians in Mumbai can send the prescription and test report, and we confirm the delivery date before the order is placed.

Bangalore

Patients in Bangalore can have the single-box course delivered to their home or treating clinic once the papers are checked.

Chennai

Infectious disease specialists in Chennai can request the capsules for a named patient through the same documented route.

Hyderabad

We share a clear timeline with Hyderabad patients up front, so the doctor can judge whether it will arrive in time.

Kolkata

For Kolkata and the eastern states, the sealed packs are shipped below 25°C and away from light.

Pune

Patients in Pune get updates at each step, from document check to doorstep delivery.

Ahmedabad

Doctors in Ahmedabad can coordinate access for adults with mild or moderate COVID-19 who need this specific medicine.

Chandigarh

Serves patients from Punjab, Haryana and Himachal Pradesh, with delivery to the patient or the treating clinic.

Jaipur

Patients across Rajasthan can receive the capsules without travelling, as long as the import is in their name.

Lucknow

We coordinate delivery to patients and hospitals across Uttar Pradesh after the prescription is verified.

Kochi

Patients across Kerala can have the course delivered to their home or clinic in Kochi and nearby cities.

Access can also be coordinated for patients in other Indian cities, subject to a valid prescription and regulatory requirements.

Author Details

Nitin Goswami

Written By

Nitin Goswami

Deputy Manager – Content & Social Media, Ikris Pharma Network

Sources: NMPA • CDSCO

Dr. Chirag C Shah

Medically Reviewed By

Dr. Chirag C Shah

MBBS

Last Updated: 19 October 2026

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