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Keverprazan

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Keverprazan

Supplied with complete CDSCO-approved import and customs documentation, including Form 12A & 12B, CDEC, GST Bill of Entry, Commercial Invoice, and Packing List.

Medicine Name: Keverprazan
Generic Name (API): Keverprazan Hydrochloride
Dosage Form & Strength: 10 mg
Route: Oral
Drug Class: Potassium-competitive acid blocker (P-CAB)

Manufacturer / Innovator:

China

Regulatory Approval:

  • NMPA (China)
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What Is Keverprazan Used For?

Keverprazan is a stomach acid blocker developed in China by Jiangsu Carephar Pharmaceutical and sold there as 倍稳® (Beiwen). It belongs to a newer group of acid-lowering medicines called potassium-competitive acid blockers, or P-CABs, and is taken as a tablet. In mainland China it is marketed together with Fosun Pharma.

China's National Medical Products Administration (NMPA) approved it in February 2023 for adults with:

  • Duodenal ulcer (an ulcer in the first part of the small intestine)
  • Reflux esophagitis (inflammation and erosions of the food pipe caused by acid reflux)

In October 2024 a third use was added: getting rid of Helicobacter pylori, the stomach bacterium behind many ulcers, when it is combined with suitable antibiotics.

It is a prescription digestive health medicine and should be used under a gastroenterologist or physician.

How It Works

The stomach makes acid with a tiny "pump" in its lining, the H+/K+-ATPase. Keverprazan blocks this pump by competing with potassium at the spot where the pump works. Unlike older proton pump inhibitors, it does not need acid to switch it on, and it can block pumps that are resting as well as those that are active. In a study in healthy volunteers, 20 mg a day kept stomach pH above 5 for 97.4% of the day by day 7.

What the Trials Showed

  • Duodenal ulcer: in a phase 3 trial of 360 patients published in Clinical and Translational Gastroenterology (2023), 94.4% of ulcers had healed by week 6 with keverprazan 20 mg, against 93.3% with a standard proton pump inhibitor. At week 4 the figures were 83.9% and 80.3%.
  • Reflux esophagitis: in a phase 3 trial of 238 patients (Alimentary Pharmacology & Therapeutics, 2022), 95.8% had healed by week 8, compared with 89.9% on a standard proton pump inhibitor.
  • H. pylori: in a phase 3 trial of 573 patients (International Journal of Antimicrobial Agents, 2024), a 14-day four-drug regimen containing keverprazan cleared the infection in 87.8% of patients, against 82.5% with a standard regimen. Among patients who completed treatment as planned, the rate was 93.5%.

Recommended Dosage

According to the Chinese prescribing information, for adults:

  • Reflux esophagitis: 20 mg once a day for 8 weeks
  • Duodenal ulcer: 20 mg once a day for 6 weeks
  • H. pylori: 20 mg twice a day, usually with amoxicillin 1,000 mg, clarithromycin 500 mg and bismuth potassium citrate 240 mg, all twice a day for 14 days

Each tablet contains 10 mg, so a 20 mg dose is two tablets. The company reports that food does not have a significant effect on how it is absorbed. Your doctor decides the exact course.

This information is not a treatment plan. For personalized medical advice, consult your doctor and refer to the full prescribing information.

Warnings and Precautions

Gastrin levels: like other strong acid blockers, it raises gastrin, a hormone the stomach releases when acid is low. In the duodenal ulcer trial the average rise was clearly higher than with the comparison medicine (195 vs 64 pg/mL), but in most patients levels returned to normal within 4 weeks of stopping.

  • Short, defined courses: the approved courses are 6 weeks for duodenal ulcer, 8 weeks for reflux esophagitis and 14 days for H. pylori. Do not continue beyond what your doctor has prescribed.
  • Liver tests: in the duodenal ulcer trial, liver changes judged to be drug-related were seen in 3.9% of patients on keverprazan (8.4% on the comparison medicine). Tell your doctor if you have liver disease.
  • Uric acid and blood fats: raised uric acid and raised blood fats were among the more common drug-related effects (2.2% each in the ulcer trial). Raised uric acid was also reported in 6.3% of patients in the H. pylori trial.
  • Stomach polyps: one serious case of stomach polyps in the ulcer trial was considered possibly related to the medicine.
  • With antibiotics: in the four-drug H. pylori regimen, the most common side effects (5% or more) were a changed sense of taste, black stools, raised uric acid and nausea. Amoxicillin and clarithromycin have their own warnings, so mention any antibiotic allergy, especially to penicillin.
  • Other medicines: give your doctor a full list of what you take, including herbal products.

Overall: in the duodenal ulcer trial, side effects of any kind occurred in 57.8% of patients on keverprazan and 59.0% on the comparison medicine, mostly mild, with no deaths. In the H. pylori trial, no serious side effects were linked to the study medicines. It is approved for adults only, and its safety in pregnancy and breastfeeding has not been established in the published data, so discuss this with your doctor first.

How to Access Keverprazan in India: A 6-Step Process

Step 1 – Search & request your medicine: The patient or treating doctor submits a request with basic details to initiate the access process.

Step 2 – Verification & eligibility review: The team verifies availability and reviews eligibility against regulatory and clinical requirements to ensure a compliant pathway.

Step 3 – Receive quote & delivery timeline: A transparent quotation is shared, covering medicine cost, logistics, and a clear delivery timeline.

Step 4 – Regulatory approval process: Assistance is provided to secure the approvals and documentation required for legal cross-border access.

Step 5 – Temperature-controlled import & handling: The medicine is sourced and transported under strict GDP-compliant conditions to maintain product integrity.

Step 6 – Secure delivery: The medicine is delivered to the patient or treating hospital, with updates provided at each stage.

Note: From request to delivery, every step is designed to ensure your treatment reaches you safely, compliantly, and without unnecessary delays.

Documentation & Availability

What documents are required to import Keverprazan to India?

The tablets can be imported only in the patient's name, by the patient or a government hospital, in line with India's import regulations for unapproved medicines. You will need:

  • A valid prescription from a qualified gastroenterologist or physician
  • Diagnostic reports, such as the endoscopy report confirming the ulcer or esophagitis, or an H. pylori test result
  • Patient ID proof (issued by the Government of India)

How is the order confirmed?

Once we have received and checked a valid prescription and, where needed, an import permit.

Is Keverprazan available in India?

No. It is approved only in China. It has no CDSCO approval, it is not sold in Indian pharmacies, and the US FDA and European Medicines Agency have not approved it either.

Patients can still get it legally through the Named Patient Program (NPP), which allows a medicine not registered in India to be imported for one specific patient on a prescription. We also arrange Anaprazole, another acid-lowering medicine approved in China for duodenal ulcer.

It can be made available to patients, doctors, and hospitals across major cities in India, including Gurgaon, Delhi, Bangalore, Mumbai, Navi Mumbai, Thane, Hyderabad, Mysore, Kerala, Chennai, Coimbatore, Madurai, Kolkata, Ahmedabad, Surat, Vadodara, Pune, Nagpur, Nashik, Jaipur, Udaipur, Lucknow, Kanpur, Gorakhpur, Chandigarh, Mohali, Faridabad, Noida, Ghaziabad, Kochi, Trivandrum, Kozhikode, Thrissur, Kannur, Mangalore, Bhubaneswar, Patna, Ranchi, Raipur, Guwahati, Visakhapatnam, Vijayawada, Goa, Jammu, Srinagar, Dehradun, Bhopal, Indore, Ludhiana, Amritsar, and others — and can facilitate delivery to the patient's treating hospital. Orders are confirmed only after receipt of a valid doctor's prescription and an import permit, where applicable.

Sourcing & Delivery

NamedPatientProgram.com (NPP) sources this medicine through the manufacturer's authorised supply channels in China and arranges supply to patients, doctors, and hospitals under applicable legal provisions. Each box holds 8 tablets of 10 mg, which is four days of treatment at 20 mg once a day. A 6-week duodenal ulcer course needs 11 boxes, an 8-week reflux esophagitis course 14 boxes, and a 14-day H. pylori course 7 boxes. The tablets travel in their sealed original packs under temperature-controlled shipping and should be stored as directed on the pack. All prescriptions are dispensed and checked by registered pharmacists and dispatched from New Delhi, India, after legal requirements are fulfilled.

For the current cost in India and availability, contact NPP via WhatsApp at +91 98104 69557 | Toll-Free: 1800-1200-365 or email info@namedpatientprogram.com.

Availability Across Major Cities in India

Patients across India can access this medicine through regulated import pathways, with delivery arranged to the patient or the treating clinic on a valid specialist's prescription.

Delhi

Gastroenterology clinics in Delhi see patients from across North India, and our New Delhi dispatch point means the tablets can reach them quickly.

Mumbai

Doctors in Mumbai can request the full course for a named patient in one order, so treatment is not interrupted halfway.

Bangalore

Patients in Bangalore can have the tablets delivered home or to their clinic once the prescription and endoscopy report are checked.

Chennai

A long-established centre for digestive medicine in South India, where specialists can share the case details with us to start the import.

Hyderabad

Gastroenterologists in Hyderabad can send the prescription and test reports, and we share a written quote before anything is ordered.

Kolkata

For Kolkata and the eastern states, we plan delivery so the course can start on the date the doctor has set.

Pune

Patients in Pune can use the same documented import route, with updates at every step.

Ahmedabad

Doctors in Ahmedabad can arrange access for patients who need this specific medicine, with the box count worked out from the prescribed course.

Jaipur

Patients from Jaipur and the rest of Rajasthan can receive the tablets at home or at their treating clinic.

Chandigarh

Serves patients from Punjab, Haryana and Himachal Pradesh, with delivery to the patient or the treating clinic.

Lucknow

We coordinate delivery to patients and hospitals across Uttar Pradesh after the paperwork is complete.

Kochi

Patients across Kerala can receive the medicine in Kochi and nearby cities.

Access can also be coordinated for patients in other Indian cities, subject to a valid prescription and regulatory requirements.

Author Details

Nitin Goswami

Written By

Nitin Goswami

Deputy Manager – Content & Social Media, Ikris Pharma Network

Sources: NMPA • CDSCO

Dr. Chirag C Shah

Medically Reviewed By

Dr. Chirag C Shah

MBBS

Last Updated: 19 October 2026

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